Multiple sclerosis (MS) is the most common neurologic disease diagnosed among young adults in whom neurons within the central nervous system are affected causing inflammation, loss of the myelin sheath, and neural degeneration. As such, many systems are potentially involved including the urinary tract. However, treatment of voiding symptoms must be individualized to each patient, taking into account the many facets of the disease, i.e., the direct effects of MS on the bladder, the ability of the patient to address those effects, the potential side effects of treatments, the complications of the disease or treatments on the ability to treat the underlying disease, and the changing nature of MS itself if the patient progresses. The purpose of this article is to review the voiding dysfunction associated with MS and its treatments relevant to the practicing urologist.
